If you are living with irritable bowel syndrome (IBS), multiple sclerosis (MS), Parkinson’s Disease, psoriasis or eczema, this medication may be of help.
Naltrexone is an FDA approved medication originally used for reversing opiate overdoses and treating alcohol dependence. However, at much lower doses, it can relieve many other conditions. LDN ( low dose naltrexone) initially binds to opiate receptors. Over time it upregulates them, increasing opiate production which helps to decrease pain, improve anxiety and depression, and even create a sense of euphoria. As an immune modulator, LDN decreases cytokines or inflammatory chemicals and helps to improve inflammatory bowel disorders (IBD), especially Crohn’s disease, and neurodegenerative conditions, like MS, Parkinson’s disease, and cognitive impairment. LDN also improves autoimmune conditions such as Hashimoto’s thyroiditis and some forms of diabetes by decreasing antibody levels. LDN can also improve allergic and dermatologic symptoms such as psoriasis and eczema. Finally, due to its ability to inhibit tumor growth, it may be helpful for various types of cancer. The earlier LDN is begun in the course of an illness, the more likely it will be helpful. Optimal benefits may not be seen till on the medication for at least 6 months, if not a full year. It is a very affordable medication, readily available. LDN is typically taken at night, but it can adversely affect sleep. Some patients find that taking it in the morning is as effective as the evening dose.
Janice Pegels, MD, MS